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Methods for analysis of O-linked modifications on epidermal growth factor-like and thrombospondin type 1 repeats

Aleksandra Nita-Lazar1, Robert S Haltiwanger

  • 1Department of Biochemistry and Cell Biology, SUNY at Stony Brook, Stony Brook, New York, USA.

Methods in Enzymology
|November 30, 2006
PubMed

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Modification of secretory and transmembrane proteins entering the rough ER begins in the ER lumen. These modifications aid in protein folding and stabilize the acquired tertiary structure. Protein modifications in the rough ER co-occur at different stages of protein folding.
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