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Updated: Jul 18, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
[Menopause - facts and controversies]
Tomasz Pertyński1, Grzegorz Stachowiak
1Department of Gynecology and Menopausal Diseases, Polish Mother Memorial Hospital, Research Institute, Lodz, Poland. gstach23@interia.pl
Abstract:
Menopausal period induces some hormonal changes in female organism. These alterations are responsible for many illnesses and ailments - e.g. disorders of menstrual cycle, climacteric symptoms, urine incontinence, connective tissue lesions, postmenopausal osteopenia and osteoporosis. All the changes negatively influence quality of life of women. The principal element of menopausal care in this period is hormone therapy (HT), alleviating many of the climacteric aliments. This article is focused also on some controversial topics concerning the HT action on breast, coronary system and brain.
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