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Updated: Jul 18, 2026

A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
[Vulvar cellular angiofibroma. A report of a case and bibliographic review]
Alejandro Hernández Monge1, Isaías Estrada Moscoso, Patricia Márquez Iribe
1Subdirección de ginecología y obstetricia, Hospital General Dr. Manuel Gea González, SSA, Mexico, DF.
Abstract:
The vulvar cellular angiofibroma is a rare mesenchymal tumor. It can be located in many places, but it is more frequent in the vulvar area. It is characterized for being of superficial and slow-growth and for having low propensity of local recurrence. It was described in 1997 by Nucci and it had been reported 51 cases worldwide, from which 18 had vulvar location. This is the first case in Mexico City. It was found in a 36 years-old woman. The specimen was processed by structural and immunohistochemical analysis. Misdiagnosis is common and it can be confounded with spindle cell lipoma, hydrocele of the canal of Nuck, fibromas, angiomyofibroblastoma and many other mesenchymal tumors. It should be distinguished from the aggresive angiomixoma. To improve the clinical diagnosis and treatment, it is very important to have in mind this relatively new entity.
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