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Multimodality Diagnosis of Mesenteric Ischemia
05:07

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

[Clinicopathologic study of ischemic intestinal disease due to mesenteric venous lesions]

Li-feng Wang1, Ming Liu, Shu-jie Zhang

  • 1Department of Pathology, First Hospital of Harbin Medical University, Harbin 150001, China. lfwy@public.hr.hl.cn

Zhonghua Bing Li Xue Za Zhi = Chinese Journal of Pathology
|December 1, 2006
PubMed
Abstract

Insights

Mesenteric phlebitis causes rare ischemic intestinal disease, characterized by venous wall inflammation and intestinal infarction. Surgical resection of the affected segment is the recommended treatment for this condition.

Area of Science:

  • Gastroenterology
  • Pathology
  • Vascular Surgery

Context:

  • Ischemic intestinal disease is a critical condition often associated with arterial compromise.
  • Mesenteric phlebitis, an inflammation of the mesenteric veins, presents a less common etiology for intestinal ischemia.
  • Understanding the unique pathological features of mesenteric phlebitis is crucial for accurate diagnosis and management.

Purpose:

  • To elucidate the clinical presentation and pathological findings of ischemic intestinal disease specifically caused by mesenteric phlebitis.
  • To describe the histopathological characteristics of venous lesions in affected patients.
  • To evaluate the outcomes following surgical intervention.

Summary:

  • This study investigated three patients with ischemic intestinal disease attributed to mesenteric phlebitis.
  • Clinical presentation included acute abdominal pain and peritonitis, with surgical findings revealing infarcted intestinal segments.
  • Histopathology demonstrated lymphocytic infiltration and fibrinoid necrosis of mesenteric veins, with mural thrombosis and subsequent intestinal infarction. Mesenteric arteries remained unaffected.
  • Follow-up in one case showed no recurrence of vasculitis.

Impact:

  • Highlights mesenteric phlebitis as a rare but distinct cause of intestinal ischemia.
  • Emphasizes the characteristic venous pathology distinct from arterial causes.
  • Supports surgical resection as a primary therapeutic strategy for this condition.

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