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Updated: Jul 18, 2026

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Two new terpenoid glucosides from Aster flaccidus.

L-S Gan1, Z-J Zhan, S-P Yang

  • 1State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, 201203, China.

Journal of Asian Natural Products Research
|December 1, 2006
PubMed
Summary

Two novel terpenoid glucosides were identified from Aster flaccidus, a traditional Chinese herb. These compounds, along with seven known ones, were characterized using advanced spectroscopic techniques.

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Area of Science:

  • Phytochemistry
  • Natural Product Chemistry
  • Medicinal Plant Research

Background:

  • Aster flaccidus (composite) is a traditional Chinese herb with a history of medicinal use.
  • The chemical constituents of Aster flaccidus are not fully elucidated.
  • Terpenoid glucosides are a class of natural products with diverse biological activities.

Purpose of the Study:

  • To isolate and characterize new chemical compounds from the aerial parts of Aster flaccidus.
  • To contribute to the understanding of the phytochemical profile of this medicinal herb.
  • To identify novel terpenoid glucosides for potential pharmaceutical applications.

Main Methods:

  • Extraction and isolation of compounds from the aerial parts of Aster flaccidus.
  • Structure elucidation using comprehensive spectroscopic methods, including 2D NMR experiments.

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  • Identification of known compounds through comparison with literature data.

    • Main Results:

    • Two new terpenoid glucosides, 2-O-beta-D-glucopyranoside-vicodiol (1) and 10-O-beta-D-glucopyranoside-oplopanone (2), were isolated and characterized.
    • Seven known compounds were also identified from the plant extract.
    • The structures of the new compounds were confirmed by detailed analysis of spectroscopic data.

    Conclusions:

    • The study successfully identified two novel terpenoid glucosides from Aster flaccidus.
    • This research expands the knowledge of the chemical constituents of this traditional Chinese herb.
    • The findings provide a basis for further investigation into the biological activities and potential applications of these compounds.