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Two new cardenolides from the roots of Streptocaulon griffithii
1Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100094, China.
Abstract:
Two new cardenolides, 3beta,5beta,14beta-trihydroxyl-card-16,20(22)-dienolide (1) and 3-O-beta-D-glucopyranosyl-5beta,14beta-dihydroxyl-card-16,20(22)-dienolide (2), together with seven known compounds identified as digitogenin (3), 16-O-acetylgitoxigenin (4), periplogenin (5), 16-O-acetylperiplogenin (6), periplogenin digitoxoside (7), periplogenin-3-O-beta-D-glucopyranoside (8) and periplogenin-3-O-beta-D-glucopyranosyl-(1-->4)-O-beta-D-digitoxopyranoside (9) were isolated from the roots of Streptocaulon griffithii. Their structures were elucidated on the basis of spectroscopic data.
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