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Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are not...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism

Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...

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A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills
07:31

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills

Published on: February 13, 2020

Student-directed learning in a community geriatrics advanced pharmacy practice experience.

Barbara L Sauer1

  • 1School of Pharmacy, University of California, San Francisco, USA. blsauer@ucdavis.edu

American Journal of Pharmaceutical Education
|December 1, 2006
PubMed
Summary

This geriatrics advanced pharmacy practice experience (APPE) improved pharmacy students' attitudes toward older adults. The program also enhanced their ability to develop and assess personal learning objectives through service-learning.

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Oral Health Assessment by Lay Personnel for Older Adults
08:47

Oral Health Assessment by Lay Personnel for Older Adults

Published on: February 2, 2020

Area of Science:

  • Geriatric Pharmacy
  • Pharmacy Education
  • Service-Learning

Background:

  • Community geriatrics experiences are crucial for pharmacy students.
  • Developing positive attitudes towards older adults is essential in geriatric care.
  • Student-directed learning enhances practical skill acquisition.

Purpose of the Study:

  • To evaluate a community geriatrics advanced pharmacy practice experience (APPE).
  • To assess the impact on students' attitudes toward older adults.
  • To evaluate the provision of a student-directed learning experience.

Main Methods:

  • A 6-week ambulatory care service-learning APPE was implemented.
  • Students provided blood pressure monitoring and medication counseling to older adults.
  • Pre- and post-experience essays were qualitatively analyzed to assess learning objectives.

Main Results:

  • Initial student perceptions of older adults were often factual or negative.
  • Students desired increased knowledge of geriatric diseases and medications.
  • Final essays indicated students gained significant humanistic insights into patient care.

Conclusions:

  • The community-based geriatrics APPE positively influenced students' attitudes.
  • The experience provided valuable practice in setting and evaluating personal learning goals.
  • This APPE fostered improved interprofessional skills and patient-centered care.