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Updated: Jul 18, 2026

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
Published on: April 7, 2015
[Ampulla cardiomyopathy induced by meningitis: two case reports]
Michifumi Kyuma1, Ryosuke Noda, Makoto Hagiwara
1Division of Cardiovascular Medicine, Muroran City General Hospital, Hokkaido. murohosp022@kujiran.jp
Meningitis can cause apical ballooning cardiomyopathy, a rare condition. This requires intensive care due to potential respiratory arrest, highlighting the importance of prompt diagnosis and management.
Area of Science:
- Cardiology
- Neurology
- Intensive Care Medicine
Background:
- Meningitis is an infection of the membranes surrounding the brain and spinal cord.
- Apical ballooning cardiomyopathy, also known as stress-induced cardiomyopathy, is typically associated with cerebrovascular disease.
- The occurrence of apical ballooning cardiomyopathy secondary to meningitis is considered rare.
Observation:
- Two patients with meningitis presented with symptoms suggestive of acute coronary syndrome, including chest pain and ST elevation.
- Coronary angiography revealed apical ballooning without significant coronary stenosis in one patient.
- Echocardiography demonstrated apical ballooning and basal hyperkinesis in the other patient, with normal creatine kinase levels.
Findings:
- The findings suggest a causal link between meningitis and the development of apical ballooning cardiomyopathy.
- This presentation is unusual, as apical ballooning cardiomyopathy is more commonly linked to cerebrovascular events.
- The absence of elevated cardiac enzymes further supports a non-ischemic etiology.
Implications:
- Meningitis should be considered as a potential trigger for apical ballooning cardiomyopathy.
- Patients with meningitis experiencing cardiac symptoms require thorough cardiovascular evaluation.
- Early recognition and intensive care are crucial due to the risk of respiratory compromise in these patients.
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