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Source: Yan, Z., et al. Evaluating the Anti-depression Effect of Xiaoyaosan on Chronically-stressed Mice. J. Vis. Exp. (2019).The video demonstrates the process of establishing a mouse model of chronic stress-induced depression and assessing depressive behaviors. The chronic application of various stressors triggers the release of corticosterone, leading to neuronal over-excitation and eventual neuronal death, which results in depression-like symptoms in the...

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Related Experiment Video

Updated: Jan 19, 2026

Animal Models of Depression - Chronic Despair Model CDM

Animal Models of Depression - Chronic Despair Model CDM

Published on: September 23, 2021

Is depression a chronic illness? For the motion

¹University of Manchester, Division of Primary Care, Rusholme Health Centre, Walmer Street, Manchester M14 5NP, UK. Linda.Gask@manchester.ac.uk

Chronic Illness

|December 2, 2006

Summary

No abstract available in PubMed .

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