Related Experiment Video
Updated: Jun 29, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Persistence of obstructive sleep apnea syndrome in children after adenotonsillectomy
Riva Tauman1, Tanya E Gulliver, Jyoti Krishna
1Kosair Children's Hospital Research Institute and the Department of Pediatrics, Division of Pediatric Sleep Medicine, University of Louisville, Louisville, Kentucky, USA.
Insights
Adenotonsillectomy improves breathing in children with obstructive sleep apnea syndrome (OSAS). However, obesity and initial apnea/hypopnea index (AHI) significantly impact surgical success, with only 25% achieving full normalization.
Area of Science:
- Pediatric Otolaryngology
- Sleep Medicine
- Respiratory Physiology
Background:
- Obstructive sleep apnea syndrome (OSAS) significantly impacts children's health.
- Adenotonsillectomy is a common treatment for pediatric OSAS.
- Predictors of surgical success require further investigation.
Purpose of the Study:
- To determine the contribution of various risk factors to adenotonsillectomy outcomes in children with OSAS.
- To assess the effectiveness of adenotonsillectomy in normalizing respiratory and sleep parameters.
Main Methods:
- Prospective study of 110 children with OSAS undergoing adenotonsillectomy.
- Two polysomnographic evaluations (pre- and post-surgery).
- Inclusion of 22 control children and collection of allergy and family history data.
Main Results:
- Significant improvements in sleep architecture and fragmentation post-surgery.
- 25% of patients achieved an apnea/hypopnea index (AHI) <=1, indicating normalization.
- Obesity was associated with a significantly lower rate of normalization (AHI <=1).
Conclusions:
- Adenotonsillectomy improves respiratory abnormalities in pediatric OSAS.
- Complete normalization of sleep parameters occurs in only 25% of patients.
- Obesity and baseline AHI are key determinants of surgical outcomes.
Objective:
To investigate the relative contribution of various risk factors to the surgical outcome of adenotonsillectomy for obstructive sleep apnea syndrome in children.
Study Design:
Children (n = 110; mean age, 6.4 +/- 3.9 years) underwent two polysomnographic evaluations before and after adenotonsillectomy. In addition, 22 control children were studied. History for allergy and family history of sleep-disordered breathing was taken before each polysomnographic evaluation.
Results:
Significant changes in sleep stage percentages and sleep fragmentation were found in the postsurgery study compared with the presurgery study; 25% of the children had apnea/hypopnea index (AHI) =1, 46% had AHI >1 and <5, and 29% had AHI >/=5 in the postsurgery study. The frequency of subjects with AHI =1 after surgery was significantly lower among obese subjects (P < .05). Comparison between the children who had AHI =1 after surgery and 22 control children showed complete normalization of sleep architecture after surgery.
Conclusions:
Adenotonsillectomy yields improvements in respiratory abnormalities in children with obstructive sleep apnea syndrome. Complete normalization occurs in only 25% of the patients. Obesity and AHI at diagnosis are the major determinant for surgical outcome. When normalization of respiratory measures occurs after surgery, normalization of sleep architecture will also ensue.
Related Concept Videos
Chronic Pharyngitis
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Tonsillitis I: Introduction
Etiology
Three primary contributing factors have been identified.
Tonsillitis II: Management
Suctioning the Nasopharyngeal Airway
Equipment Required
Suctioning the Oropharyngeal Airway
After assembling the equipment, the nurse should practice hand hygiene and don appropriate PPE according to infection control guidelines to avoid the...
Sleep Apnea
The condition is more prevalent among...

