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Updated: Jul 18, 2026

Integration of Brain Tissue Saturation Monitoring in Cardiopulmonary Exercise Testing in Patients with Heart Failure
Published on: October 1, 2019
Exercise-induced desaturation and electrocardiogram changes in people with severe lung disease: an exploratory
Alice Y M Jones1, Wai-Cho Yu, Ngai-Shing Mok
1Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong.
Background:
Arterial desaturation is a commonly accepted clinical basis for discontinuing physical activity in people with chronic obstructive pulmonary disease.
Objective:
The purpose of this exploratory study was to examine the electrocardiograms of people with severe chronic obstructive pulmonary disease recovering from exercise-induced arterial desaturation.
Subjects:
Subjects (n = 25) walked for 6 minutes while oxygen saturation was monitored.
Methods:
When the Spo2 decreased below 90%, subjects were asked to sit and rest while the electrocardiograms were recorded. For all patients, Spo2 decreased 11.6% on average below baseline during walking. Four patients developed dysrhythmias during desaturation, with a mean lowest Spo2 of 85%. The Spo2 in six other patients continued to decrease below 80% despite rest, yet these patients did not develop new dysrhythmias.
Conclusions:
Our findings suggest that a decrease in Spo2 during exercise does not necessarily correlate with cardiac rhythm.
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