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Updated: Jul 18, 2026

Measuring Local Anaphylaxis in Mice
Published on: October 14, 2014
Midventricular hypokinesis as a cardiac manifestation of anaphylaxis: a case report
1Division of Cardiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA. yhan@bidmc.harvard.edu
Abstract:
We report a case of anaphylaxis in which left midventricular hypokinesis was found by echocardiogram performed while the patient was hypotensive shortly after the onset of acute chest pain with S-T segment elevations. Cardiac injury was confirmed by elevation of cardiac enzymes. Repeated echocardiogram 2 days later demonstrated normal ventricular wall function and coronary angiogram demonstrated no angiographically apparent disease. We discuss possible mechanisms for cardiac injury and suggest mast cell-mediated coronary spasm as the most likely.
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