[Effects of reperfusion on late potentials of the QRS complex in acute myocardial infarction]

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Confirmation of Myocardial Ischemia and Reperfusion Injury in Mice Using Surface Pad Electrocardiography
09:23

Confirmation of Myocardial Ischemia and Reperfusion Injury in Mice Using Surface Pad Electrocardiography

Published on: November 24, 2016

Radomir Matunović1, Zoran Cosić, Dragan Tavciovski

  • 1Klinika za kardiologiju, Vojnomedicinska akademija, Beograd. matun@eunet.yu

Medicinski Pregled
|December 5, 2006
PubMed

Insights

Signal-averaged electrocardiogram (SAECG) detects late potentials, indicating unsuccessful reperfusion after myocardial infarction. This finding predicts artery patency in acute myocardial infarction patients treated with thrombolytics.

Area of Science:

  • Cardiology
  • Electrophysiology

Context:

  • Cardiac rhythm disorders are common post-myocardial infarction (MI).
  • Signal-averaged electrocardiogram (SAECG) identifies patients at risk for ventricular tachycardia.
  • Early reperfusion of the infarct-related artery improves outcomes.

Purpose:

  • To investigate the association between QRS complex late potentials (SAECG) and reperfusion success in acute myocardial infarction (AMI) patients.
  • To determine if SAECG late potentials predict infarct-related artery patency.

Summary:

  • SAECG was assessed in 33 AMI patients receiving reperfusion therapy.
  • Late potentials were present in 26.1% of patients with successful reperfusion versus 80% with unsuccessful reperfusion.
  • A significant association was found between SAECG late potentials and unsuccessful reperfusion.

Impact:

  • SAECG late potentials are significantly associated with unsuccessful reperfusion in AMI.
  • Late potentials serve as an independent predictor of infarct-related artery patency in AMI patients undergoing thrombolytic therapy.
Abstract

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