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Laparoscopic-assisted double-balloon enteroscopy for small-bowel polyp surveillance and treatment in patients with
Andrew S Ross1, Charles Dye, Vivek N Prachand
1Current affiliations: Section of Endoscopy and Therapeutics and Section of General Surgery, The University of Chicago Hospitals, Chicago, Illinois, USA.
Insights
Laparoscopic-assisted double-balloon enteroscopy (LADBE) offers a promising single-procedure solution for managing small-bowel polyps in Peutz-Jeghers syndrome (PJS) patients. This technique facilitates complete surveillance and polyp resection, improving patient care.
Area of Science:
- Gastroenterology
- Surgical Innovation
- Genetics
Background:
- Peutz-Jeghers syndrome (PJS) presents challenges in small-bowel polyp surveillance and treatment.
- Existing methods like double-balloon enteroscopy (DBE) may necessitate multiple procedures for complete enteroscopy.
Observation:
- A retrospective review evaluated laparoscopic-assisted DBE (LADBE) for PJS patients with small-bowel polyps.
- The study focused on a single North American tertiary-care center.
Findings:
- LADBE enabled complete enteroscopy and endoscopic resection of all polyps >0.5 cm in three PJS patients.
- Procedure times ranged from 1 to 4 hours, with no cancer or dysplasia detected.
- Postoperative ileus occurred in two patients.
Implications:
- LADBE demonstrates potential as a unified surveillance and therapeutic strategy for small-bowel polyps in PJS.
- This technique may enhance the management of PJS-related gastrointestinal complications.
Background:
Surveillance and treatment of small-bowel polyps in patients with Peutz-Jeghers syndrome (PJS) can be challenging and may require intraoperative enteroscopy. While initial reports that used double-balloon enteroscopy (DBE) for the resection of small-bowel polyps in patients with PJS appear promising, complete enteroscopy when using this technique may require multiple procedures or may not be possible at all.
Objective:
To develop a single-procedure approach to the surveillance and the treatment of small-bowel polyps in patients with PJS.
Design:
Retrospective review.
Setting:
Single, North American tertiary-care center.
Patients:
Individuals with PJS and small-bowel polyps identified by other modalities.
Interventions:
DBE was combined with laparoscopy as a single-procedure surveillance and therapeutic strategy for small-bowel PJS polyps.
Main Outcome Measurements:
Completion of enteroscopy, number of polyps resected, procedure duration, complications.
Results:
Three patients with a history of PJS and known small-bowel polyps underwent laparoscopic-assisted DBE (LADBE). Complete enteroscopy was performed, and all polyps larger than 0.5 cm were resected endoscopically. No cases of cancer or dysplasia were noted; procedure times lasted from 1 to 4 hours. Postoperative complications included ileus in 2 patients.
Limitations:
Small sample size, single-center experience.
Conclusions:
LADBE holds promise as a new technique that can be used as both a surveillance and a therapeutic tool for small-bowel polyps in patients with PJS.
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