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Epithelioid angiosarcoma of the small bowel
Jaber Al Ali1, Hin Hin Ko, David Owen
1Divisions of Gastroenterology, Vancouver General, Hospital and University of British Columbia, Vancouver, BC, Canada.
Gastrointestinal Endoscopy
|December 5, 2006
Summary
Epithelioid angiosarcoma is a rare cancer found in the gastrointestinal tract and skin. This aggressive cancer has a poor prognosis, with a median survival of only two months after diagnosis.
Area of Science:
- Oncology
- Gastroenterology
- Pathology
Background:
- Angiosarcoma is a rare soft-tissue neoplasm, typically affecting the skin and subcutaneous tissues.
- Intestinal angiosarcoma is exceptionally rare, posing diagnostic and therapeutic challenges.
Observation:
- A case of multifocal epithelioid angiosarcoma involving both skin and bowel is presented.
- The patient exhibited anemia, skin nodules, and positive fecal occult blood tests.
- Enteroscopy revealed ulcerated nodules in the duodenum and jejunum, confirmed as epithelioid angiosarcoma on biopsy.
Findings:
- Epithelioid angiosarcoma of the intestine has a poor survival rate, with a median survival of approximately two months post-diagnosis.
- The infiltrative and multifocal nature of this malignancy often precludes complete surgical resection.
Implications:
- Early diagnosis and multimodal treatment strategies are crucial for improving outcomes in intestinal angiosarcoma.
- Further research is needed to determine the efficacy of adjuvant therapies, such as radiation and chemotherapy.
