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The prevalence of cardiovascular risk factors among centenarians is low: risk factors in centenarians
Jolanta Zyczkowska1, Alicja Klich-Raczka, Barbara Wizner
1Department of Internal Medicine and Gerontology, Jagiellonian University Medical College, Cracow, Poland.
Insights
Centenarians exhibit a superior cardiovascular risk profile compared to middle-aged adults, with lower rates of smoking, overweight, and hypercholesterolemia. This suggests that exceptional longevity is associated with reduced cardiovascular risk factors.
Area of Science:
- Gerontology
- Cardiovascular Health
- Epidemiology
Background:
- Investigating major cardiovascular risk factors in centenarians.
- Assessing the prevalence of key risk factors in extreme longevity.
Purpose of the Study:
- To compare the cardiovascular risk profiles of centenarians with a younger, middle-aged cohort.
- To determine the association between longevity and cardiovascular risk factors.
Main Methods:
- Analysis of cardiovascular risk factors (sex, smoking, overweight, diabetes, hypertension, hypercholesterolemia) in 93 centenarians.
- Comparison with data from 90 individuals aged 40-60 years.
Main Results:
- Smoking, overweight, and hypercholesterolemia were more prevalent in the younger group.
- Hypertension was diagnosed more frequently in centenarians.
- 55.4% of centenarians had zero or one risk factor, versus 14.2% in the younger group.
Conclusions:
- Centenarians possess a significantly better cardiovascular risk profile than middle-aged individuals.
- Longevity appears strongly linked to a favorable cardiovascular risk profile.
- Reduced exposure to common cardiovascular risks may facilitate extreme aging.
Background:
The presence of major cardiovascular risk factors was investigated in a group of centenarians.
Methods:
The following risk factors: sex, smoking, overweight, diabetes, hypertension and hypercholesterolemia were analysed in 93 centenarians and compared with data obtained from 90 individuals age 40-60 years.
Results:
Smoking, overweight and hypercholesterolemia were found statistically more often in a younger population, whereas hypertension was diagnosed more frequently in centenarians. No or one risk factor were found in 55.4% of centenarians and in 14.2% of younger subjects.
Conclusions:
Centenarians are characterized by a much better cardiovascular risk profile than middle-aged individuals. This indicates that longevity is related to low cardiovascular risk.
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