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Updated: Jul 18, 2026

Expression, Detergent Solubilization, and Purification of a Membrane Transporter, the MexB Multidrug Resistance Protein
10:43

Expression, Detergent Solubilization, and Purification of a Membrane Transporter, the MexB Multidrug Resistance Protein

Published on: December 3, 2010

RALBP1/RLIP76 mediates multidrug resistance

Kenneth J Drake1, Jyotsana Singhal, Sushma Yadav

  • 1Department of Chemistry and Biochemistry, University of Texas at Arlington, Arlington, TX 76019-0065, USA.

International Journal of Oncology
|December 5, 2006
PubMed
Summary

Overexpression of RLIP76/RALBP1 transporter confers multidrug resistance in K562 leukemia cells. Inhibiting this transporter increases chemotherapy drug efficacy, suggesting it as a therapeutic target for leukemia treatment.

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