Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Adipose tissue: a subtle and complex cell system].

Béatrice Cousin1, Sylvie Caspar-Bauguil, Valérie Planat-Bénard

  • 1IFR31, Institut Louis Bugnard, UMR 5018 CNRS UPS, BP 84225, 31432 Toulouse 4, France. cousinb@toulouse.inserm.fr

Journal De La Societe De Biologie
|December 6, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Regenerative repair is connected to early and specific structural, immune, and metabolic MSC signatures in adult mammals.

Scientific reports·2026
Same author

Periodontitis therapy using autologous adipose-derived stromal cells: a double-blind randomized controlled clinical trial in an aged canine model.

Cytotherapy·2026
Same author

Expert-guided multi-objective optimization: An efficient strategy for parameter estimation of biological systems with limited data.

Bio Systems·2026
Same author

Age-related evolution of human gingiva towards a fibrotic-like connective phenotype.

Scientific reports·2025
Same author

Alterations in peroxisome-mitochondria interplay in skeletal muscle accelerate muscle dysfunction.

Nature communications·2025
Same author

EMito-Metrix enables automated evaluation of mitochondrial morphology across species.

Nature metabolism·2025
Same journal

[Food safety of GMOs].

Journal de la Societe de biologie·2010
Same journal

[Placing on the market, breeders rights and growing genetically modified (GM) varieties].

Journal de la Societe de biologie·2010
Same journal

[Cultivation and environmental impacts of GMO crops].

Journal de la Societe de biologie·2010
Same journal

[Applications of genetically modified animals].

Journal de la Societe de biologie·2010
Same journal

[Why GMOs].

Journal de la Societe de biologie·2010
Same journal

[Mutations in renin-angiotensin system genes and kidney developmental anomalies].

Journal de la Societe de biologie·2010
See all related articles

White adipose tissue (WAT), once viewed as inert, is a dynamic source of stem cells. These cells, derived from the stromal vascular fraction (SVF), show potential for diverse therapeutic applications.

Area of Science:

  • Adipose tissue biology and stem cell research.

Context:

  • White adipose tissue (WAT) was historically considered metabolically inactive and primarily studied for its role in energy balance and endocrine functions.
  • WAT comprises mature adipocytes and the stromal vascular fraction (SVF), which contains distinct stromal and hematopoietic compartments.
  • Recent characterization reveals the stromal population, termed Adipose Derived Stromal Cells (ADAS), exhibits macrophage-like features and multipotent differentiation capabilities.

Purpose:

  • To explore the multifaceted nature of white adipose tissue beyond its metabolic roles.
  • To highlight the potential of adipose-derived stem cells for therapeutic applications.
  • To underscore the plasticity and heterogeneity of WAT as a source of regenerative medicine.

Summary:

  • WAT is a complex, heterogeneous tissue containing various cell subsets with potential for differentiation into multiple cell types, including cardiomyocytes, osteoblasts, and neural cells.

Related Experiment Videos

  • The stromal vascular fraction (SVF) of WAT yields Adipose Derived Stromal Cells (ADAS), which possess stem cell properties and can differentiate in vitro and in vivo.
  • The ease of sampling and inherent plasticity of WAT make it a promising source for stem cell therapies.

    • Impact:

    • Reclassifies white adipose tissue as a highly plastic and heterogeneous tissue with significant regenerative potential.
    • Establishes WAT as a valuable and accessible source for stem cell isolation, advancing cell therapy research.
    • Opens new avenues for understanding adipose tissue biology and its therapeutic applications.