Related Experiment Video
Updated: Jul 18, 2026

Investigating the Protective Effects of Platycodin D on Non-Alcoholic Fatty Liver Disease in a Palmitic Acid-Induced In Vitro Model
Published on: December 2, 2022
[Chemical constituents from roots of Platycodon grandiflorum]
Ling-Jun Li1, Zhen-Hua Liu, Yun Chen
1Department of Chinese Medicine Science and Engineering, Zhejiang University, Hangzhou 310028, China.
Objective:
To study the chemical constituents from roots of Platycodon grandiflorum.
Method:
Column chromatography (silica gel, macroporous resin, sephadex LH - 20 and the preparative RP - HPLC were used to isolate the constituents. Their structures were elucidated by physical and spectral data.
Result:
Eight compounds were isolated and identified as tangeritin (1), 3-O-beta-D-glucopyranosylplatycodigenin methyl ester (2), 3-O-beta-D-glucopyranosylplaticogenic acid A lactone (3), 3-O-beta-D-glucopyranosylplatycodigenin (4), deapio-platyconic acid A lactone (5), deapio-platycodin-D (6), platycoside-G1 (7) and platycoside-E (8).
Conclusion:
Compounds 1,3 and 5 were isolated from this plant for the first time.
Related Concept Videos
Basic Plant Anatomy: Roots, Stems, and Leaves
Water and Mineral Acquisition
Plant Tissues
