[Age-related specificity of the blood picture in females with diffuse toxic goiter]

The factor analysis was used to examine a relationship of a number of clinical and blood biochemical parameters to the level of triiodothyronine (T3), tyroxine (T4), and thyroid-stimulating hormone (TSH) in third-fourth degree diffuse toxic goiter (DTG) in females aged 17-45 and 46-58 years. It was established that the changes in T4 and TSH values were coordinated and T3 values varied independently. In DTG, the concentration of T4 correlated with that of K' and the levels of TSH and T4 correlated with those of cholesterol only in the age group less than 45 years. The specific features of the leukogram were associated with the level of T4 in females aged under 45 years and with that of TSH in females over 45 years of age. In DTG, there was a drop in blood TSH concentrations only in the group of 46-59 years.