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Related Experiment Video

Updated: Jul 18, 2026

Workflow and Tools for Crystallographic Fragment Screening at the Helmholtz-Zentrum Berlin
06:29

Workflow and Tools for Crystallographic Fragment Screening at the Helmholtz-Zentrum Berlin

Published on: March 3, 2021

Experimental fragmentation studies with 12C therapy beams.

E Haettner1, H Iwase, D Schardt

  • 1Biophysik, Gesellschaft für Schwerionenforschung, Planckstr.1, D-64291 Darmstadt, Germany. e.haettner@gsi.de

Radiation Protection Dosimetry
|December 6, 2006
PubMed
Summary

This study investigated carbon ion (12C) beam fragmentation in water, crucial for precise radiotherapy. Understanding these secondary fragments improves radiation dose delivery for deep-seated tumors.

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Area of Science:

  • Medical Physics
  • Particle Therapy
  • Radiation Oncology

Background:

  • Carbon ion (12C) beams are utilized in radiotherapy for treating deep-seated tumors.
  • Accurate physical data is essential for optimizing dose deposition and treatment planning.

Purpose of the Study:

  • To experimentally investigate the fragmentation characteristics of 12C ions in a water phantom.
  • To enhance the physical database for carbon ion radiotherapy.

Main Methods:

  • Used high-energy 12C ion beams (80-430 MeV u(-1)) from the SIS-18 synchrotron.
  • Employed a water phantom as a tissue-equivalent absorber.
  • Identified secondary fragments (Z(f) = 1-5) using scintillation detectors with DeltaE-E and time-of-flight techniques at specific depths and energies (200 and 400 MeV u(-1)).

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Main Results:

  • Measured energy and angular distributions of secondary fragments.
  • Determined fragment yields, build-up curves, and attenuation of primary carbon projectiles.
  • Provided preliminary data on the physical interactions of 12C ions in tissue-equivalent material.

Conclusions:

  • The experimental data contributes to a more precise physical database for carbon ion radiotherapy.
  • Understanding fragmentation is key to improving treatment planning and efficacy for localized tumors.
  • Further analysis will refine the understanding of secondary particle transport in biological tissues.