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Related Experiment Videos

DADOS-Prospective: an open source application for Web-based prospective data collection.

Lam Nguyen1, Anand Shah, Matthew Harker

  • 1School of Medicine, University of North Carolina-Chapel Hill, Chapel Hill, NC 27599, USA. ngoc-lam_nguyen@med.unc.edu

Source Code for Biology and Medicine
|December 7, 2006
PubMed
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DADOS-Prospective is an open-source web application designed to streamline data management for multi-center clinical trials. This tool facilitates efficient data collection, quality control, and regulatory file storage, proving effective in prospective studies.

Area of Science:

  • Clinical Research
  • Translational Science
  • Health Informatics

Background:

  • Multi-institutional clinical and translational research relies heavily on robust data management systems.
  • Coordinating multi-center studies presents challenges in data collection, quality control, and communication.
  • Existing systems often lack integrated solutions for diverse data management needs.

Purpose of the Study:

  • To introduce DADOS-Prospective, an open-source web application for managing prospective human subject data in clinical trials.
  • To highlight the application's capabilities in creating clinical research forms (CRF), supporting electronic signatures, and centralizing data and documentation.
  • To present DADOS-Prospective as a solution to the complexities of multi-center data management.

Main Methods:

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  • The DADOS-Prospective application was designed and developed based on formal and field usability testing feedback.
  • The system is a web-based, open-source application.
  • It allows for the creation of customizable CRFs and supports electronic signatures.

Main Results:

  • DADOS-Prospective has been successfully implemented in five prospective clinical studies at the institution.
  • One study has been fully launched, while four are in the CRF creation phase.
  • The application integrates raw data, source documents, regulatory files, and audit trails in a single environment.

Conclusions:

  • DADOS-Prospective offers significant advantages over existing web-based data collection programs.
  • It has proven to be an efficient tool for managing prospective clinical studies.
  • The open-source nature and comprehensive features make it a valuable asset for multi-institutional research.