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Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
Published on: December 11, 2017
[Comparative analysis of the risk factor on the clinical information of myocardial revascularization combined with
Jun-sheng Mu1, Jian-qun Zhang, Ping Bo
1Department of Cardiac Surgery, Affiliated Anzhen Hospital of Capital University of Medical Sciences, Beijing 100029, China. wesleymu@hotmail.com
Insights
Coronary artery bypass grafting (CABG) combined with valve surgery is safe. However, female patients face higher morbidity and mortality risks, linked to lower weight and mitral valve stenosis.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Surgical Outcomes
Context:
- Combined coronary artery bypass grafting (CABG) and valve operations are complex procedures.
- Understanding sex-based differences in outcomes is crucial for patient management.
Purpose:
- To evaluate clinical information and outcomes of patients undergoing combined CABG and valve surgery.
- To identify potential risk factors influencing morbidity and mortality in this patient cohort.
Summary:
- A retrospective analysis of 126 patients revealed significant differences in clinical characteristics between sexes, including weight, diabetes, mitral valve stenosis, and coronary artery disease severity.
- Morbidity and mortality rates, as well as the number of bypass grafts and mitral valve replacements, showed significant sex-based variations.
- Female patients experienced higher rates of complications and mortality, with specific causes including heart failure, arrhythmia, and organ failure.
Impact:
- Female gender emerged as an independent risk factor for increased morbidity and mortality post-surgery.
- Lower body weight and the presence of mitral valve stenosis in females contribute to adverse outcomes.
- Findings underscore the need for tailored perioperative strategies for female patients undergoing combined cardiac procedures.
Objective:
To evaluate the clinic information of coronary artery bypass grafting (CABG) combined with concomitant valve operation.
Methods:
Retrospectively analyze the information of morbidity and mortality of 126 cases patients who underwent combined valve and bypass procedures between December 2000 and January 2005. These patients had been divided into 2 groups according to sex.
Results:
There were significant differences in the clinic characteristic such as weight and diabetes mellitus and mitral valve stenosis and three disease vessels of coronary artery between 2 groups (P < 0.05). The rate of the number of bypass grafts and morbidity and mortality of complication were significant differences (P < 0.05). The number of mitral valve replacement of female was more than that of male (P < 0.05). Five males died after operation, 1 case of heart failure, 1 case of high blood sugar, 2 cases of arrhythmia, 2 cases of organs failure; Seven females died after operation, one case of heart failure, one case of alimentary tract haemorrhage, three cases of arrhythmia, two cases of organs failure.
Conclusions:
Coronary artery bypass grafting (CABG) combined with concomitant valve operation is safe and effective. The rate of morbidity and mortality of complication of female is more than that of male. The study demonstrates that female gender is an independent risk factor for combined morbidity and mortality during and after combined valve and coronary bypass surgery. That is related to low weight and mitral valve stenosis of female.
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