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Ensembl 2007.

T J P Hubbard1, B L Aken, K Beal

  • 1Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK. th@sanger.ac.uk

Nucleic Acids Research
|December 7, 2006
PubMed
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This summary is machine-generated.

The Ensembl project now offers 33 chordate genome sequences, including new mammalian and fish genomes. Recent updates feature complete gene sets, strain variation data, and orthology annotations for enhanced genomic research.

Area of Science:

  • Genomics
  • Bioinformatics

Background:

  • The Ensembl project serves as a crucial resource for chordate genome annotation.
  • Expanding genomic data is essential for comparative genomics and evolutionary studies.

Purpose of the Study:

  • To report the expansion of the Ensembl database with new genome sequences and features.
  • To highlight advancements in genomic annotation and data integration.

Main Methods:

  • Integration of 33 chordate genome sequences into the Ensembl database.
  • Development of new gene sets for low-coverage genomes.
  • Implementation of strain variation data and orthology/paralog annotations.

Main Results:

  • The Ensembl database now includes 33 genomes, with 18 new additions, including diverse mammalian and fish species.

Related Experiment Videos

  • Complete gene sets were generated for previously underrepresented genomes.
  • New orthology and paralogy annotations were introduced, based on gene tree analysis.

    • Conclusions:

    • The Ensembl project continues to grow, providing a more comprehensive resource for genomic research.
    • These updates facilitate deeper insights into genome evolution and function across chordates.