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DNBS/TNBS Colitis Models: Providing Insights Into Inflammatory Bowel Disease and Effects of Dietary Fat
Published on: February 27, 2014
Nutrition and inflammatory load
M D Kontogianni1, A Zampelas, C Tsigos
1Department of Nutrition and Dietetics, Laiko Hospital, 11527 Athens, Greece.
Annals of the New York Academy of Sciences
|December 7, 2006
Summary
Chronic inflammation contributes to metabolic diseases. This review examines nutrients and dietary patterns, like the Mediterranean diet, that modulate inflammation and protect against conditions such as atherothrombosis and type 2 diabetes.
Area of Science:
- Nutrition Science
- Immunology
- Metabolic Disease Research
Background:
- Chronic inflammation is linked to metabolic diseases like atherothrombosis and type 2 diabetes.
- Nutrients (fatty acids, antioxidants, etc.) and dietary patterns influence immune responses.
- The Mediterranean diet shows promise for cardiovascular protection due to anti-inflammatory effects.
Purpose of the Study:
- To review the pro- and anti-inflammatory properties of various nutrients.
- To explore dietary patterns that mitigate chronic inflammation.
- To discuss protection against metabolic and atherothrombotic complications.
Main Methods:
- Literature review of existing data on nutrient and dietary pattern effects on inflammation.
- Analysis of scientific evidence regarding immunomodulatory properties.
- Synthesis of findings on chronic inflammation and metabolic diseases.
Main Results:
- Specific nutrients possess both pro- and anti-inflammatory characteristics.
- Dietary patterns, notably the Mediterranean diet, demonstrate significant anti-inflammatory potential.
- Evidence supports a role for diet in managing inflammation-related metabolic disorders.
Conclusions:
- Dietary interventions targeting nutrient profiles and patterns can combat chronic inflammation.
- Modulating inflammation through diet may offer protection against metabolic diseases and atherothrombosis.
- Further research into specific dietary strategies is warranted for disease prevention.
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