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Updated: Jul 18, 2026

A Novel Murine Model of Arteriovenous Fistula Failure: The Surgical Procedure in Detail
Published on: February 3, 2016
Insufficient arteriovenous fistulae in hemodialysis patients
1Unilabs Mittelland, Institut fur Pathologie, Bern, Switzerland. jkr.janzen@freenet.de
Background:
For an accurate assessment of structural changes in arteriovenous fistulae (AVF) a microscopic analysis is mandatory.
Methods:
25 insufficient AVF were analyzed with the light microscope using standard histological and immunohistochemical techniques.
Results:
In 7 patients (28%) atherosclerotic lesions as causes of AVF insufficiency were found. The other 18 patients (72%) had an inhomogeneous spectrum of nonatherosclerotic lesions, for instance intimal hyperplasia.
Conclusions:
Histopathologic analysis of insufficient AVF helps clarify the underlying changes in the structure of the vessel wall.
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