[Invasive therapeutic strategies in acute heart failure complicating coronary artery disease: effectiveness and boundaries]
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Published on: February 3, 2021
Tudor C Poerner1, Markus Ferrari, Bernhard R Brehm
1Klinik für Innere Medizin I, Friedrich-Schiller-Universität, Erlanger Allee 101, 07747, Jena. tpoerner@googlemail.com
Insights
Acute myocardial infarction (MI) with cardiogenic shock can be fatal. Mechanical circulatory support devices and revascularization improve survival by stabilizing patients for procedures like percutaneous coronary intervention.
Area of Science:
- Cardiology
- Cardiovascular Surgery
- Critical Care Medicine
Context:
- Acute myocardial infarction (MI) frequently leads to cardiogenic shock, a life-threatening condition.
- Despite advancements, cardiogenic shock remains a significant cause of mortality in acute MI patients.
- Mechanical reperfusion via percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) surgery is crucial for survival.
Purpose:
- To provide an overview of therapeutic strategies for acute MI with cardiogenic shock.
- To highlight the role of mechanical circulatory support devices in managing these critical patients.
- To discuss the specific applications and benefits of various support devices.
Summary:
- Acute heart failure and cardiogenic shock are common causes of death in acute myocardial infarction (MI).
- Mechanical reperfusion through PCI or CABG surgery significantly improves survival rates in patients with acute MI and cardiogenic shock.
- Intraaortic balloon pump (IABP) support and ventricular assist devices are vital for hemodynamic stabilization, enabling safe revascularization procedures.
Impact:
- Improved patient outcomes in acute MI complicated by cardiogenic shock.
- Enhanced understanding of mechanical circulatory support device selection and utilization.
- Guidance for clinicians on optimizing therapeutic strategies for high-risk MI patients.
Abstract:
Acute heart failure and especially its most severe form, cardiogenic shock, remain the final common pathway to death in a substantial number of patients with acute myocardial infarction (MI). Several studies demonstrated that mechanical reperfusion of occluded coronary arteries by percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) surgery improves survival in patients with acute MI and cardiogenic shock. There is strong evidence that intraaortic balloon pump (IABP) support and ventricular assist devices can stabilize hemodynamics in these patients so that revascularization procedures can be safely performed. This article provides an overview of the therapeutic strategies for acute MI with cardiogenic shock, with focus on the role and particularities of different devices used as mechanical circulatory support in these patients.
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