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Spinal arachnoid calcifications.

Coen A Wijdicks1, James M Williams

  • 1Department of Anatomy and Cell Biology, Rush Medical College, Rush University Medical Center, Chicago, Illinois 60612, USA.

Clinical Anatomy (New York, N.Y.)
|December 7, 2006
PubMed
Summary
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Calcified arachnoid plaques were found in a cadaver

Area of Science:

  • Neuroscience
  • Pathology
  • Anatomy

Background:

  • Arachnoid calcifications are often asymptomatic findings.
  • Previous causes include trauma, myelography, hemorrhage, and spinal anesthesia.
  • Calcified plaques can be precursors to spinal arachnoid ossificans.

Purpose of the Study:

  • To describe calcified arachnoid plaques in a cadaver.
  • To histologically confirm the composition of the plaques.

Main Methods:

  • An 86-year-old male cadaver was dissected.
  • A laminectomy was performed from C4 to the lumbo-sacral junction.
  • Calcified plaques were identified, measured, and stained with Von Kossa and Alizarin Red S.

Main Results:

Related Experiment Videos

  • Multiple calcified arachnoid plaques were identified in the dorsal thoracic region (T2-T3, T7, T9).
  • Plaques measured 1.0 mm in thickness and 0.5-1.0 cm in diameter.
  • Staining confirmed the presence of calcium phosphate and calcium.

Conclusions:

  • Calcified arachnoid plaques are incidental findings in cadavers.
  • These plaques did not cause spinal cord or nerve root compression in this case.
  • Arachnoid calcifications may represent a precursor to spinal arachnoid ossificans.