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Related Concept Videos

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
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The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
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Antiasthma Drugs: Leukotriene Modifiers01:19

Antiasthma Drugs: Leukotriene Modifiers

Leukotriene modifiers, or cysteinyl leukotriene receptor antagonists, are medications used to manage chronic asthma. These agents target specific inflammatory mediators produced during arachidonic acid metabolism, an essential process in generating inflammation in the body.
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Drugs Used in Lower Respiratory Disorders: Overview01:17

Drugs Used in Lower Respiratory Disorders: Overview

Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
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Related Experiment Video

Updated: Jul 18, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Targeted interventions for difficult-to-treat asthma.

Bradley E Chipps1, Julia M Harder

  • 1Capital Allergy & Respiratory Disease Center, Sacramento, CA 95819, USA. bchipps@capitalallergy.com

Expert Opinion on Therapeutic Targets
|December 8, 2006
PubMed
Summary

Managing chronic persistent asthma remains challenging for many patients. This review explores barriers to asthma control and discusses advanced strategies and therapies for difficult-to-treat cases.

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Last Updated: Jul 18, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

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Published on: November 4, 2010

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System
07:28

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Area of Science:

  • Pulmonology
  • Allergy and Immunology
  • Pharmacology

Background:

  • Chronic persistent asthma significantly impacts patient quality of life and healthcare costs.
  • Current guideline-directed therapy effectively manages most asthma cases, but approximately one-third of patients require additional interventions.

Purpose of the Study:

  • To review barriers to achieving and maintaining asthma control.
  • To discuss strategies for managing difficult-to-treat asthma.
  • To explore newer and developing therapies for specific asthma phenotypes.

Main Methods:

  • Literature review of current asthma management guidelines and research.
  • Analysis of factors contributing to suboptimal asthma control.
  • Examination of emerging therapeutic approaches and biomarkers.

Main Results:

  • Barriers include inaccurate assessment measures, patient response variability, and poor adherence.
  • Biomarkers offer potential for improved asthma control assessment.
  • Novel therapies are being developed for specific patient subgroups with severe asthma.

Conclusions:

  • Addressing barriers to asthma control is crucial for improving patient outcomes.
  • Personalized treatment strategies utilizing biomarkers and novel therapies show promise for difficult-to-treat asthma.
  • Continued research is needed to optimize management for all asthma patients.