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Updated: Jul 18, 2026

A Microplate Assay to Assess Chemical Effects on RBL-2H3 Mast Cell Degranulation: Effects of Triclosan without Use of an Organic Solvent
Published on: November 1, 2013
Triclosan
Lauren Campbell1, Matthew J Zirwas
1Department of Dermatology, University of Pittsburgh, PA, USA.
Abstract:
Triclosan is a common antibacterial chemical currently in widespread use in household and health care-related products. Triclosan was first introduced in 1965 and has been marketed as cloxifenol, Irgasan CH 3565, and Irgasan DP 300. Its most common use is in antimicrobial hand soaps, but in the United States it can also be found in consumer products such as liquid dishwashing soaps, deodorants, and toothpastes. The concentrations used in products in the United States typically range from 0.15 to 0.3%. While allergy to triclosan-based products is uncommon, several cases of contact dermatitis secondary to triclosan have been reported.
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