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Related Concept Videos

Epistaxis01:30

Epistaxis

Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...

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Related Experiment Video

Updated: Jul 18, 2026

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement
08:50

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

Published on: March 26, 2018

Severe aortic valve stenosis and nosebleed.

Johannes Schödel, Achim Obergfell, Alexander H Maass

    International Journal of Cardiology
    |December 8, 2006
    PubMed
    Summary

    Severe epistaxis (nosebleeds) in patients with aortic valve stenosis may signal acquired von Willebrand syndrome. This condition, marked by a loss of von Willebrand factor multimers, can cause significant bleeding and warrants consideration for valve replacement surgery.

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    Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
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    Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

    Published on: May 21, 2017

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    Last Updated: Jul 18, 2026

    Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement
    08:50

    Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

    Published on: March 26, 2018

    Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
    12:17

    Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

    Published on: May 21, 2017

    Area of Science:

    • Cardiology
    • Hematology

    Background:

    • Aortic valve stenosis is linked to acquired von Willebrand syndrome.
    • This syndrome can cause bleeding, particularly gastrointestinal bleeding in Heyde syndrome.

    Observation:

    • A patient presented with anemia and severe epistaxis.
    • No gastrointestinal bleeding source was identified via endoscopy.
    • Echocardiography confirmed calcifying aortic stenosis.

    Findings:

    • Immunoblot analysis revealed a loss of high molecular weight multimers of von Willebrand factor.
    • This confirmed acquired von Willebrand syndrome in the patient.

    Implications:

    • Severe epistaxis in symptomatic aortic valve stenosis patients may indicate acquired von Willebrand syndrome.
    • This finding suggests valve replacement surgery as a potential treatment option for such cases.