Related Experiment Video
Updated: Jul 18, 2026

Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus
Published on: January 28, 2019
[Nosocomial rotavirus infections in a pediatric unit: surveillance during four successive winters]
E Marc1, S Biscardi, M Soulier
1Service de Pédiatrie Générale, 2 ter, rue d'Alésia, Hôpital Saint-Vincent-de-Paul-Cochin, 75014 Paris, France.
Insights
Nosocomial rotavirus infections were highly prevalent in Parisian pediatric units, affecting 13.9% of infants. Young age and longer hospital stays increased infection risk, highlighting the need for improved infection control measures.
Area of Science:
- Pediatric Infectious Diseases
- Hospital Epidemiology
- Virology
Context:
- Winter outbreaks of rotavirus and RSV cause pediatric unit overcrowding in Paris.
- Overcrowding escalates the risk of viral nosocomial infections in hospitalized infants.
Purpose:
- To quantify the incidence of nosocomial rotavirus infections in children under two years old over four consecutive winters.
Summary:
- Prospective screening identified a 13.9% incidence of nosocomial rotavirus infection.
- Asymptomatic rotavirus carriage was observed in 3% of infants.
- Increased risk was associated with younger age and prolonged hospitalization.
Impact:
- Findings indicate a high rate of nosocomial rotavirus infections in the studied pediatric unit.
- Coinciding outbreaks and patient demographics contribute to infection transmission.
- Highlights the need for enhanced infection control strategies in pediatric settings during peak viral seasons.
Unlabelled:
The incidence of rotavirus and RSV outbreaks during winter seasons leads to overcrowding of pediatric units in the Paris area, and increases the risk of viral nosocomial infections in hospitalized young infants.
Objective:
The aim of this study was to measure the incidence of rotavirus nosocomial infections in children less than 2 years of age during 4 consecutive winters.
Methods:
All infants admitted in the pediatric unit during the winter were prospectively screened for rotavirus with a stools exam. All children with negative stools examination on admission but developing diarrhea after 2 days of hospitalization underwent a new screening test for rotavirus in stools.
Results:
During the 4 consecutive winters, the global incidence of nosocomial rotavirus infection was 13.9% (12.7 to 15.9%). Asymptomatic carriage of rotavirus was detected in 3% of admitted infants. The risk of nosocomial rotavirus infection increases with young age and the length of hospital stay.
Conclusion:
The incidence of nosocomial rotavirus infections was high in this unit. It is related to overcrowding due to coincidence of diarrhea and bronchiolitis outbreaks in the Paris area and to the young age of hospitalized patients.
Related Concept Videos
Respiratory Syncytial Virus Disease
Bacterial Gastroenteritis
Poliomyelitis
Viral Meningitis
Investigation of Disease Outbreaks
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
