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Hedgehog Signaling Pathway Database: a repository of current annotation efforts and resources for the Hh research
Kieran Hervold1, Andrew Martin, Roger A Kirkpatrick
1Department of biology, Cell and Biology Group and Center for Computing in Life Sciences, San Francisco State University, 1600 Holloway Avenue, 738 Hensill Hall, San Francisco, CA 94132, USA.
Abstract:
The Hedgehog Signaling Pathway Database is a curated repository of information pertaining to the Hedgehog developmental pathway. It was designed to provide centralized access to a wide range of relevant information in an organism-agnostic manner. Data are provided for all genes and gene targets known to be involved in the Hh pathway across various organisms. The data provided include DNA and protein sequences as well as domain structure motifs. All known human diseases associated with the Hh pathway are indexed including experimental data on therapeutic agents and their molecular targets. Hh researchers will find useful information on relevant protocols, tissue cell lines and reagents used in current Hh research projects. Curated content is also provided for publications, grants and patents relating to the Hh pathway. The database can be accessed at http://www.hedgehog.sfsu.edu.
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