Changing outcomes of coronary revascularization in British Columbia, 1995-2001
Gordon E Pate1, Min Gao, Lillian Ding
1Interventional Cardiology Research, St Paul's Hospital, Vancouver. gordon.pate@galwayclinic.com
Insights
Percutaneous coronary intervention (PCI) use increased, with improved 30-day survival for both PCI and coronary artery bypass graft surgery (CABG). Emergent CABG saw reduced mortality, while PCI showed fewer repeat procedures within a year.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Health Services Research
Background:
- Coronary revascularization procedures, including coronary artery bypass graft surgery (CABG) and percutaneous coronary intervention (PCI), are critical treatments for coronary artery disease.
- Understanding the comparative outcomes of CABG and PCI in real-world clinical practice is essential for guiding treatment decisions.
Purpose of the Study:
- To evaluate and compare the outcomes of all first-time coronary revascularization procedures, specifically isolated CABG and PCI, in adults residing in British Columbia between 1995 and 2001.
Main Methods:
- Data for CABG and PCI procedures were sourced from the British Columbia Cardiac Registry.
- Mortality data were obtained from the British Columbia Vital Statistics Agency.
- Analysis involved annual cohorts, reporting unadjusted rates for PCI and CABG outcomes.
Main Results:
- PCI utilization increased significantly from 62% in 1995 to 73% in 2001.
- Thirty-day mortality improved for both PCI (1.8% to 1.1%) and CABG (1.8% to 1.2%), except in emergent cases.
- Emergent cases, predominantly treated by PCI, showed no change in mortality, while emergent CABG mortality substantially decreased (28% to 10%).
- One-year survival free from repeat revascularization improved for PCI (73% to 83%) but showed minimal change for CABG (94% to 95%).
Conclusions:
- Observed improvements in procedure-related mortality from clinical trials are reflected in current clinical practice.
- While PCI use increased for emergent cases without a change in mortality, CABG demonstrated a significant reduction in emergent case mortality.
- Patients undergoing PCI experienced a consistent and substantial decrease in the need for repeat procedures within one year.
Objectives:
To examine outcomes following all first coronary revascularization procedures, isolated coronary artery bypass graft surgery (CABG) and percutaneous coronary intervention (PCI) on British Columbia (BC) resident adults from 1995 to 2001.
Methods:
CABG and PCI data were obtained from the BC Cardiac Registry, and mortality data were obtained from the BC Vital Statistics Agency. Analysis was performed by annual cohorts, and the rates reported are unadjusted.
Results:
An increasing percentage of revascularization procedures was performed with PCI (62% in 1995 to 73% in 2001; P<0.001) due to the increased use of PCI procedures. Except in emergent cases, 30-day mortality improved after PCI (1.8% to 1.1%; P=0.02) and CABG (1.8% to 1.2%; P=0.01). Emergent cases accounted for 9.0% of PCIs and 2.7% of CABGs, the percentage treated by CABG decreasing from 14.5% in 1995 to 7.5% by 2001 (P<0.001). Mortality rates among emergent cases was higher at 30 days, with no trend in PCI mortality (12%) but a substantial reduction in 30-day mortality after CABG (28% to 10%; P=0.003). One-year survival free from repeat revascularization following PCI increased from 73% in 1995 to 83% in 2001 (P<0.001) and from 94% to 95% (P<0.005) following CABG.
Conclusions:
Improvements in procedure-related mortality observed in trials have extended to clinical practice. With respect to emergent cases, an increasing proportion were treated by PCI with no change in PCI mortality but associated with a drop in surgical mortality. There has been a consistent and substantial drop in the need for repeat procedures within one year for patients selected for PCI.
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