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Related Experiment Video

Updated: Jul 18, 2026

Drawing Blood from Rats through the Saphenous Vein and by Cardiac Puncture

Drawing Blood from Rats through the Saphenous Vein and by Cardiac Puncture

Published on: August 23, 2007

[Leonardo Botallo, de via sanguinis].

Mariacarla Gadebusch Bondio¹

¹Ernest Moritz Arndt Universität Greifswald Institut für Geschichte der Medizin, D.

Medicina Nei Secoli

|December 13, 2006

Summary

Seventeenth-century anatomists Cecilio Folli and L. Botallo republished a treatise on the foramen ovale. They argued, influenced by Aristotelian philosophy, that this heart structure persists in adults, challenging prevailing views.

Area of Science:

Anatomy
History of Medicine
Cardiovascular Physiology

Background:

This study examines the 17th-century anatomical work of Cecilio Folli, focusing on his republication of L. Botallo's treatise concerning the foramen ovale.
The research highlights the historical debate surrounding the persistence of the foramen ovale in adult human anatomy.

Discussion:

Folli and Botallo, adhering to Aristotelian philosophy, supported the view that the foramen ovale remains present in adults.
This perspective contrasted with contemporary anatomical understanding and influenced the discourse on fetal circulation and cardiac anatomy.

Key Insights:

The foramen ovale, a fetal heart structure, was controversially believed by Folli and Botallo to persist into adulthood.
The influence of Aristotelian philosophy on 17th-century anatomical theories is evident in their work.

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Outlook:

Further historical research can illuminate the broader impact of Folli's and Botallo's theories on subsequent anatomical studies.
Understanding historical anatomical debates provides context for the evolution of modern cardiovascular science.