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Updated: Jul 18, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
[Blood transfusion: history ethic and law]
Paola Frati1, Gianluca Montanari Vergallo, Natale Mario Di Luca
1Dipartimento di Medicina Legale, II Facoltà di Medicina e Chirurgia, Università degli Studi di Roma "La Sapienza", I. paola.frati@uniroma1.it
Abstract:
The paper outlines the stages of the history of blood transfusion from the earlier attempts and difficulties to the important discoveries of the early XX century and to recent developments, that have made blood transfusion an easy life-saving method. The authors also examine the ethical motivations underlying transfusion refusal as well as the economical measures of solidarity contained in the Italian law n. 210/1992 to protect HIV HCV or HBV patients, especially those having contracted infection because of mandatory vaccinations or infected blood transfusions.
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