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Updated: Jul 18, 2026

Induction of Microstreaming by Nonspherical Bubble Oscillations in an Acoustic Levitation System
Published on: May 9, 2021
Interaction between shock wave and single inertial bubbles near an elastic boundary
1Department of Mechanical Engineering and Materials Science, Duke University, Durham, North Carolina 27708, USA.
Abstract:
The interaction of laser-generated single inertial bubbles (collapse time = 121 mus) near a silicon rubber membrane with a shock wave (55 MPa in peak pressure and 1.7 mus in compressive pulse duration) is investigated. The interaction leads to directional, forced asymmetric collapse of the bubble with microjet formation toward the surface. Maximum jet penetration into the membrane is produced during the bubble collapse phase with optimal shock wave arrival time and stand-off distance. Such interaction may provide a unique acoustic means for in vivo microinjection, applicable to targeted delivery of macromolecules and gene vectors to biological tissues.
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