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Updated: Jul 18, 2026

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Published on: June 9, 2023
Increasing thyroid cancer incidence in Lithuania in 1978-2003
Giedre Smailyte1, Edita Miseikyte-Kaubriene, Juozas Kurtinaitis
1Institute of Oncology, Vilnius University, Division of Cancer Prevention, Polocko 2, Vilnius, Lithuania. gsmailyte@gmail.com
Thyroid cancer incidence in Lithuania increased moderately from 1978-2000, then accelerated significantly by 2003. This rise in thyroid cancer is linked to improved diagnostic methods for thyroid nodules.
Area of Science:
- Epidemiology
- Oncology
- Public Health
Background:
- Analyzing thyroid cancer incidence trends in Lithuania from 1978-2003.
- Focusing on changes observed between 1993-2003.
Purpose of the Study:
- To analyze changes in thyroid cancer incidence trends in Lithuania.
- To identify significant shifts in these trends using joinpoint regression.
Main Methods:
- Utilized data from the Lithuanian Cancer Registry (1978-2003).
- Calculated age-specific and standardized incidence rates using the world standard population.
- Applied joinpoint regression to estimate annual percentage changes and detect trend shifts.
Main Results:
- Age-standardized incidence rates rose from 0.7 to 2.5 (males) and 1.5 to 11.4 (females) per 100,000.
- Joinpoint analysis revealed a trend shift in 2000, indicating a dramatic increase.
- Increases in papillary carcinoma and Stage I thyroid cancer drove recent trend changes.
Conclusions:
- Observed a moderate increase in thyroid cancer incidence (1978-2000).
- Documented an accelerated rise in incidence from 2000-2003.
- Attributed the increase to enhanced diagnosis of non-palpable thyroid nodules via ultrasound-guided fine needle aspiration biopsy.
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