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Rituximab induced hypoglycemia in non-Hodgkin's lymphoma
Badrudeen M Hussain1, N Geetha, V Lali
1Division of Surgical Oncology, Regional Cancer Centre, Thiruvananthapuram, Kerala, India. hussain@rcctvm.org
Background:
Hypoglycemia is a vary rare toxicity of rituximab. The exact mechanism of rituximab induced hypoglycemia is not clear.
Case Presentation:
A 50 year old female presented with a left tonsillar non Hodgkin's lymphoma and was started on R-CHOP chemotherapy. Twenty four hours after the first rituximab infusion, she developed hypoglycemia which was managed by IV glucose infusion.
Conclusion:
Hypoglycemia following rituximab administration is rare. Possibilities of hypoglycemia should be kept in mind in patients developing symptoms like fatigue, restlessness, and sweating while on rituximab therapy.
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