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Related Experiment Video

Updated: Jul 18, 2026

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer
11:17

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer

Published on: February 27, 2026

Sublobar resections for lung cancer.

Ryan C Fields1, Bryan F Meyers

  • 1Division of Cardiothoracic Surgery, Barnes-Jewish Hospital, Washington University Medical Center, St. Louis, Missouri 63110-1013, USA.

Seminars in Thoracic and Cardiovascular Surgery
|December 13, 2006
PubMed
Summary

Sublobar resection is an option for early-stage lung cancer in patients with poor lung function. While early data showed higher recurrence, current evidence on oncologic and pulmonary outcomes compared to lobectomy is mixed.

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Area of Science:

  • Thoracic Surgery
  • Surgical Oncology
  • Pulmonary Medicine

Background:

  • Sublobar resection is an alternative to lobectomy for early-stage lung cancer, particularly in patients with compromised pulmonary function.
  • Initial studies indicated higher local recurrence and mortality rates with sublobar resection compared to lobectomy.
  • Subsequent research presents mixed findings regarding the comparative outcomes of these surgical approaches.

Purpose of the Study:

  • To review existing literature comparing sublobar resection and lobectomy for early-stage lung cancer.
  • To evaluate oncologic and pulmonary outcomes associated with each surgical method.
  • To discuss the role of adjuvant intraoperative brachytherapy in sublobar resection and summarize relevant clinical trials.

Main Methods:

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Subcostal Specimen Removal in Completely Portal Robotic Lobectomy
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Subcostal Specimen Removal in Completely Portal Robotic Lobectomy

Published on: April 19, 2024

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Last Updated: Jul 18, 2026

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer
11:17

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer

Published on: February 27, 2026

Subcostal Specimen Removal in Completely Portal Robotic Lobectomy
04:38

Subcostal Specimen Removal in Completely Portal Robotic Lobectomy

Published on: April 19, 2024

  • Systematic literature review of studies comparing sublobar resection and lobectomy.
  • Analysis of oncologic outcomes (e.g., recurrence rates) and pulmonary function.
  • Review of data on adjuvant intraoperative brachytherapy and ongoing clinical trials.

    • Main Results:

    • Evidence comparing sublobar resection to lobectomy for early-stage lung cancer shows mixed results regarding oncologic and pulmonary outcomes.
    • The role and efficacy of adjuvant intraoperative brachytherapy in conjunction with sublobar resection require further investigation.
    • Ongoing clinical trials are actively comparing sublobar resection with and without adjuvant brachytherapy.

    Conclusions:

    • Sublobar resection may be considered for select early-stage lung cancer patients with poor pulmonary function, but outcomes require careful consideration.
    • Further research and evidence from ongoing trials are crucial for refining recommendations on sublobar resection versus lobectomy.
    • The integration of adjuvant brachytherapy warrants continued evaluation in the context of sublobar resection for lung cancer treatment.