The Amblyopia and Strabismus Questionnaire: English translation, validation, and subscales

Area of Science:

• Ophthalmology
• Psychometrics
• Vision Science

Background:

• Amblyopia and strabismus significantly impact patient quality of life.
• Validated patient-reported outcome measures are essential for clinical research and practice.
• The original Dutch Amblyopia and Strabismus Questionnaire (ASQE) required an English translation for broader use.

Purpose of the Study:

• To establish the English-language version of the Amblyopia and Strabismus Questionnaire (ASQE).
• To assess the psychometric properties of the translated ASQE in an adult population.

Main Methods:

• A prospective cohort study involving 150 adults with strabismus and/or amblyopia.
• A structured translation process was employed to create the English ASQE.
• Participants completed the ASQE, a disability questionnaire, and underwent clinical characterization.

Main Results:

• The English ASQE demonstrated high internal consistency reliability (Cronbach's alpha 0.80-0.92).
• ASQE scores showed strong correlations with disability questionnaire outcomes (r = -0.76, P < .0001).
• Significant correlations were observed between ASQE scores and clinical characteristics.

Conclusions:

• The English ASQE possesses good psychometric properties, consistent with the original Dutch version.
• The ASQE is a reliable and valid instrument for assessing the impact of strabismus and amblyopia.
• The validated ASQE serves as a valuable tool for clinical populations with these visual conditions.