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Updated: Jul 18, 2026

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia
Published on: September 22, 2020
[Choice of surgical treatment method for patients with critical lower limb ischemia]
Abstract:
A new method for study of microcirculation potency and tissue viability in patients with critical lower limb ischemia is described. Microcirculation resistance was studied with dynamic scintigraphy which shows primary passage of radiopharmaceutical into microcirculatory system. Accumulation of radiopharmaceutical associated with necrotic and inflammatory zones was detected with static scintigraphy. Results of surgical treatment have been studied in 105 of 123 examinees. Based of these data the criteria of lower limb microcirculation efficacy and tissue viability have been elaborated. Significant value of these two criteria in assessment of efficacy of various types of revascularization and amputations is demonstrated.
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