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Related Experiment Video

Updated: Jul 18, 2026

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
05:34

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

5-Year outcomes of laparoscopic partial nephrectomy.

Brian R Lane1, Inderbir S Gill

  • 1Section of Laparoscopic and Robotic Surgery, Glickman Urological Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

The Journal of Urology
|December 13, 2006
PubMed
Summary

Laparoscopic partial nephrectomy offers excellent long-term oncological and renal functional outcomes for small renal masses. This study confirms its efficacy with a 5-year follow-up, showing minimal recurrence and high survival rates.

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Area of Science:

  • Urology
  • Surgical Oncology
  • Nephrology

Background:

  • Laparoscopic partial nephrectomy (LPN) is a standard treatment for small renal masses.
  • Intermediate-term oncological outcomes for LPN are well-established up to 3 years.
  • Long-term data (5+ years) on LPN outcomes are less frequently reported.

Purpose of the Study:

  • To evaluate the oncological and renal functional outcomes of LPN after a minimum of 5 years.
  • To assess the long-term efficacy and safety of LPN for localized renal tumors.
  • To compare LPN outcomes with established results from open partial nephrectomy.

Main Methods:

  • Retrospective review of 56 patients who underwent LPN for localized renal tumors and completed at least 5 years of follow-up.
  • Data collected included clinical information, renal function (serum creatinine), and oncological outcomes (recurrence, survival).

Related Experiment Videos

Last Updated: Jul 18, 2026

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
05:34

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

  • Patients were contacted via telephone for updated information.

    • Main Results:

    • The study included 56 patients with a mean age of 64 years; 66% had renal cell carcinoma, with 86% staged as pT1a.
    • At a median follow-up of 5.7 years, no distant recurrence was observed, and only one local recurrence (2.7%) occurred.
    • Overall survival was 86%, and cancer-specific survival was 100%. Renal function remained stable, with no cases of chronic renal insufficiency in patients with normal baseline creatinine.

    Conclusions:

    • Laparoscopic partial nephrectomy demonstrates excellent and durable oncological control for small renal masses over 5 years.
    • Renal function is well-preserved after LPN, comparable to open partial nephrectomy.
    • LPN is a safe and effective established alternative to open partial nephrectomy for selected patients.