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Related Concept Videos

Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
Major Hormones and Their Functions01:27

Major Hormones and Their Functions

Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and lactation.
Accessory Structures of the Skin: Sebaceous Glands01:21

Accessory Structures of the Skin: Sebaceous Glands

A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
Gonadal and Placental Hormones01:24

Gonadal and Placental Hormones

The gonads, namely the testes in males and the ovaries in females, are pivotal in producing gonadal hormones that orchestrate the intricate processes of sexual development and reproduction.
In males, testosterone is the primary gonadal androgen. It plays a central role in the maturation of male reproductive organs — the penis and testes. Additionally, testosterone is instrumental in the development of secondary sexual characteristics — a deep voice as well as facial and pubic hair growth — and...
Oogenesis02:07

Oogenesis

In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
Oogenesis01:22

Oogenesis

Oogenesis,  the process of developing egg cells (female gametes), occurs within the ovaries and is fundamental to female fertility. This sequence begins during fetal development when diploid oogonia in the developing ovaries undergo mitotic divisions to produce primary oocytes. By birth, these primary oocytes enter prophase I of meiosis but become arrested in this stage, remaining suspended until puberty.
Each primary oocyte is surrounded by a layer of pre-granulosa cells, forming what is known...

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Related Experiment Video

Updated: Jul 18, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
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Published on: August 13, 2019

Oestrogens and the skin.

Mark P Brincat1

  • 1University of Malta, Malta. thedean@keyworld.net

Journal of Cosmetic Dermatology
|December 14, 2006
PubMed
Summary

Menopause-related oestrogen loss impacts skin. Hormone replacement therapy (HRT) shows promise for improving skin collagen, thickness, and elasticity, but effects on other skin aspects require further research.

Area of Science:

  • Dermatology
  • Endocrinology
  • Gerontology

Background:

  • Oestrogen decline during menopause significantly affects skin structure and function.
  • Previous research indicates oestrogen influences key skin components like collagen and elasticity.

Purpose of the Study:

  • To examine the multifaceted effects of oestrogen and hormone replacement therapy (HRT) on menopausal skin.
  • To synthesize existing data on HRT's impact on skin aging and repair.

Main Methods:

  • Review of physiological studies on oestrogen and skin.
  • Analysis of data concerning HRT's effects on collagen, dermal thickness, elasticity, and water content.
  • Assessment of discordant findings regarding elastin, sebaceous secretions, wrinkling, and blood flow.

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Detecting Estrogenic Ligands in Personal Care Products using a Yeast Estrogen Screen Optimized for the Undergraduate Teaching Laboratory
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Prospecting Microbial Strains for Bioremediation and Probiotics Development for Metaorganism Research and Preservation
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Prospecting Microbial Strains for Bioremediation and Probiotics Development for Metaorganism Research and Preservation

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An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause

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Detecting Estrogenic Ligands in Personal Care Products using a Yeast Estrogen Screen Optimized for the Undergraduate Teaching Laboratory
14:13

Detecting Estrogenic Ligands in Personal Care Products using a Yeast Estrogen Screen Optimized for the Undergraduate Teaching Laboratory

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09:49

Prospecting Microbial Strains for Bioremediation and Probiotics Development for Metaorganism Research and Preservation

Published on: October 31, 2019

Main Results:

  • Oestrogen treatment consistently increases collagen, dermal thickness, and elasticity in post-menopausal women.
  • Evidence suggests potential benefits of HRT for skin water content and wound healing.
  • Inconsistent results were observed for elastin content, sebaceous secretions, wrinkling, and skin blood flow.

Conclusions:

  • Oestrogen significantly influences skin aging, with HRT showing benefits for specific skin parameters.
  • Further molecular-level investigations are necessary to fully elucidate oestrogen's cellular mechanisms in skin.
  • Additional research is warranted to clarify the variable effects of HRT on diverse skin characteristics.