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Nonopioid analgesics.

Muhammad A Munir1, Nasr Enany, Jun-Ming Zhang

  • 1Department of Anesthesiology, University of Cincinnati College of Medicine, 231 Albert Sabin Way, PO Box 67031, Cincinnati, OH 45267-0531, USA. munirma@ucmail.uc.edu

The Medical Clinics of North America
|December 14, 2006
PubMed
Summary
This summary is machine-generated.

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Nonsteroidal anti-inflammatory drugs (NSAIDs) are effective pain relievers for inflammatory conditions. Their routine use should be considered for acute, chronic, and cancer-related pain, especially postoperatively, barring contraindications.

Area of Science:

  • Pharmacology
  • Pain Management
  • Inflammation

Background:

  • Nonsteroidal anti-inflammatory drugs (NSAIDs) are established analgesics.
  • Their application in managing postoperative and chronic pain is often underutilized.
  • Inflammation is a key component in many pain states where NSAIDs are beneficial.

Purpose of the Study:

  • To highlight the efficacy of NSAIDs in various pain conditions.
  • To advocate for the routine consideration of NSAIDs in pain management protocols.
  • To address the underuse of NSAIDs in specific patient populations.

Main Methods:

  • Literature review on NSAID efficacy.
  • Analysis of NSAID use in acute, chronic, cancer, and noncancer pain.
  • Examination of contraindications for NSAID therapy.

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Main Results:

  • NSAIDs demonstrate significant analgesic properties, particularly in inflammatory pain.
  • Underutilization noted in postoperative and chronic pain management.
  • Routine consideration is recommended when no contraindications exist.

Conclusions:

  • NSAIDs are valuable therapeutic options for a wide spectrum of pain.
  • Clinicians should routinely consider NSAIDs for acute pain, chronic pain (cancer and noncancer), and postoperative pain management.
  • Patient-specific contraindications must be assessed prior to NSAID initiation.