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Updated: Jul 18, 2026

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
Published on: November 2, 2013
Vitamin D receptor genotypes/haplotypes and prostate cancer risk
Mine S Cicek1, Xin Liu, Fredrick R Schumacher
1Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Ohio, USA.
Abstract:
The vitamin D receptor (VDR) gene has been associated with prostate cancer, although previous results are somewhat equivocal. To further study this, we did a family-based case-control study (N = 918) of the association between prostate cancer and six common VDR variants: Cdx2, FokI, BsmI, ApaI, TaqI, and the poly-A microsatellite. Looking at each variant alone, only FokI and ApaI were associated with disease. The FokI FF genotype was inversely associated with prostate cancer among men with less advanced disease (i.e., Gleason score <7 and tumor stage
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