Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Male hormonal contraception].

I Porsová-Dutoit1

  • 1Silinkův nadaení fond, Praha. praha.korunovacni@atlas.cz

Vnitrni Lekarstvi
|December 15, 2006
PubMed
Summary

Male hormonal contraception (MHC) aims to suppress sperm production while maintaining male sexual function and health. Promising methods combine testosterone with long-acting progestins for effective male fertility regulation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Place of inhibin B investigation in clinical andrological praxis].

Vnitrni lekarstvi·2008
Same author

Do DHEA/DHEAS play a protective role in coronary heart disease?

Physiological research·2000
Same author

[The Internet and medicine. I. Historical development, current organizational structure, E-mail, the Web and discussion forums].

Vnitrni lekarstvi·1998
Same author

[The Internet and medicine. II. Present status and perspectives in the use of the Internet in Medicine].

Vnitrni lekarstvi·1998
Same author

[Thyroglobulin and microsome autoantibodies and their clinical significance in adult type I diabetics].

Vnitrni lekarstvi·1996
Same author

Glycoprotein hormone alpha-subunit secretion in prolactinomas and in non-functioning adenomas: relation with the tumour size.

Clinical endocrinology·1994

Area of Science:

  • Reproductive endocrinology
  • Andrology
  • Pharmacology

Context:

  • Human reproduction research is a multidisciplinary effort.
  • Developing novel male contraceptive methods is a global health priority.
  • The World Health Organization (WHO) actively supports research in male fertility regulation.

Purpose:

  • To review the principles and current status of male hormonal contraception (MHC).
  • To explore various MHC formulations and their underlying mechanisms.
  • To identify future research directions for effective male contraception.

Summary:

  • Male hormonal contraception (MHC) suppresses spermatogenesis by inhibiting gonadotropin (FSH and LH) secretion, primarily through testosterone administration.
  • MHC strategies include testosterone monotherapy (oral, injectable, transdermal, subcutaneous) or combined with progestins, antiandrogens, or GnRH analogues.
  • Current research highlights depot testosterone combined with long-acting progestins as a highly promising MHC approach.

Impact:

  • Establishes the scientific basis for male hormonal contraception development.
  • Provides a comprehensive overview of existing and emerging MHC strategies.
  • Outlines criteria for future MHC clinical success: efficacy, reversibility, safety, acceptability, and cost-effectiveness.

Related Experiment Videos