Related Experiment Video
Updated: Jul 18, 2026

Two-Dimensional Visualization and Quantification of Labile, Inorganic Plant Nutrients and Contaminants in Soil
Published on: September 1, 2020
The total synthesis of tubulysin D
Hillary M Peltier1, Jeffrey P McMahon, Andrew W Patterson
1Department of Chemistry, University of California, Berkeley, California 94720, USA.
Abstract:
The first total synthesis of tubulysin D is reported. The development and application of new tert-butanesulfinamide methods allowed for rapid syntheses of the tubuvaline and tubuphenylalanine fragments. Most significantly, a route was devised and implemented to introduce and carry forward the highly labile N,O-acetal functionality. Tubulysin D is the most active member of the tubulysin family, and the efficient synthetic route described herein will allow for the rapid syntheses of analogues to probe the biological activity of this important class of natural products.
More Related Videos
09:16Optimization of Processing Technology for Tiebangchui with Zanba Based on CRITIC Combined with Box-Behnken Response Surface Method
Published on: May 12, 2023
09:12Optimization of Processing of Tiebangchui with Highland Barley Wine Based on the Box-Behnken Design Combined with the Entropy Method
Published on: May 19, 2023
Related Concept Videos
Chemical Formulas
Formula Mass and Mole Concepts of Compounds
Experimental Determination of Chemical Formula
Mixtures of Gases: Dalton's Law of Partial Pressures and Mole Fractions
Resultant of a General Distributed Loading
Examples such as load distribution due to wind and load distribution on a bridge illustrate how this concept is used to analyze and design safe, reliable structures under variable loading conditions. Most structures, such as residential buildings, bridges, and towers, are...
Combining Functions