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Aging of hair
1Department of Dermatology and Hair Consultation Clinic, University Hospital of Zurich, Switzerland. ralph.trueeb@usz.ch
Journal of Cosmetic Dermatology
|December 15, 2006
Summary
Hair aging involves shaft weathering and follicle changes like graying and hair loss. Oxidative stress contributes to aging, with treatments like minoxidil and finasteride available for hair loss.
Area of Science:
- Dermatology and Cosmetology
- Hair Biology and Aging Research
Background:
- Hair appearance significantly impacts self-perception and the desire for youthful looks.
- The hair care and pharmaceutical industries are developing advanced products and drugs for hair maintenance.
- Hair aging encompasses both hair shaft weathering and hair follicle aging, leading to graying and hair loss.
Purpose of the Study:
- To review the multifaceted aspects of hair aging, including intrinsic and extrinsic factors.
- To discuss current and emerging therapeutic strategies for managing hair aging and related conditions.
- To highlight the role of oxidative stress in the aging process of hair and scalp.
Main Methods:
- Literature review of scientific studies on hair aging mechanisms and treatments.
- Analysis of intrinsic factors (genetics, epigenetics) and extrinsic factors (UV radiation, smoking).
- Examination of the role of oxidative stress and potential anti-aging compounds.
Main Results:
- Hair follicle aging results in decreased melanocyte function (graying) and reduced hair production (alopecia).
- Intrinsic factors like genetics and extrinsic factors like UV exposure contribute to scalp and hair aging.
- Oxidative stress is implicated in skin and hair aging processes.
Conclusions:
- Current treatments for androgenetic alopecia include minoxidil, finasteride, and hair transplantation.
- Hair colorants are used to address graying, while novel topical delivery systems are under investigation.
- Understanding hair aging is crucial for developing effective anti-aging hair care and therapeutic strategies.
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