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Updated: Jul 18, 2026

Assessment of Oxidative Damage in the Primary Mouse Ocular Surface Cells/Stem Cells in Response to Ultraviolet-C (UV-C) Damage
Published on: February 15, 2020
Digital ultraviolet reflectance photography can be used to quantify improvements in photodamage
B M Freedman1, R V Earley, T P Balakrishnan
1Plastic Surgery Associates of Northern Virginia 22102, USA. bfreedman58@aol.com
Objective:
Increasing attention has focused on the treatment and reversal of ultraviolet- induced photodamage. This study was designed to determine whether ultraviolet reflectance photography could quantify the clinical effects of erbium:YAG laser resurfacing on photoaged skin.
Methods:
Twenty patients (ages 46-67) with moderate to severe photodamage underwent dual-mode variable pulsed erbium:YAG laser facial resurfacing. Pretreatment and post-treatment evaluations at 3 and 6 months were performed clinically and photographically with white and ultraviolet reflectance photography.
Results:
Image conversion of the ultraviolet reflectance imaging data demonstrated an average of 36% and 42% reduction in photodamage at 3 and 6 months, respectively. This correlated well with the wrinkle reduction and correction of dyspigmentation observed in all patients following laser resurfacing. Histologic examination confirmed a thicker, more orderly epidermis and dermal collagen remodeling after treatment.
Conclusion:
Reduction in photodamage using the dual-mode variable pulsed erbium:YAG laser can be quantitatively measured with ultraviolet reflectance photography using digital imaging. This model should prove useful in developing treatment regimens for photodamage.
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